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posted on 2021-03-08, 18:39 authored by Michael G. Dorrington, Clinton J. Bradfield, Justin B. Lack, Bin Lin, Jonathan J. Liang, Tregei Starr, Orna Ernst, Julia L. Gross, Jing Sun, Alexandra H. Miller, Olivia Steele-Mortimer, Iain D. C. Fraser

A) WT and Ifnar1-/- iBMDMs were infected with GFP+ Burkholderia thailandensis, as in Fig 2D, for 22 h. Bacterial replication was measured by mean GFP fluorescence in the infected population. B, C, D) WT and Ifnar1-/- iBMDMs were infected with dsRed+ Bc, as in Fig 2F and 2B) The total number of cells imaged, C) the total spot area per cell, and D) the number of live cells per imaged field are enumerated. All experiments were performed with n ≥ 3, and are shown as representative of 2 independent experiments. * = p≤0.05 and *** = p≤0.001 by Mann-Whitney U test.

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