ppat.1009395.s001.tif (336.83 kB)
S1 Fig -
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posted on 2021-03-08, 18:39 authored by Michael G. Dorrington, Clinton J. Bradfield, Justin B. Lack, Bin Lin, Jonathan J. Liang, Tregei Starr, Orna Ernst, Julia L. Gross, Jing Sun, Alexandra H. Miller, Olivia Steele-Mortimer, Iain D. C. FraserA, B) WT (JAX 664) and Ifnar1-/- mice were injected with 10mg/kg LPS, as in Fig 1C, and survival was tracked over 5 days. A) presents three separate experiments (n ≥ 5 per genotype) while B) shows these three experiments combined. C) Litter-matched WT and Ifnar1-/- mice were infected with 5x106 CFUs of wt J2315, as in Fig 1D. Broncho-alveolar lavages were performed and cytokines were measured using a LegendPLEX anti-viral cytokine assay.
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