pone.0277692.g005.tif (926.1 kB)
Rebamipide inhibits adipogenesis in vitro.
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posted on 2022-12-27, 18:31 authored by JooYeon Jhun, Jeonghyeon Moon, Se-Young Kim, Keun-Hyung Cho, Hyun Sik Na, JeongWon Choi, Yoon Ju Jung, Kyo Young Song, Jun-Ki Min, Mi-La Cho(A) Adipocyte differentiation of 3T3-L1 was inhibited by rebamipide. (B) Expression of adipogenesis-related genes such as adiponectin, leptin, lipoprotein lipase (LPL) and adipocyte protein 2 (aP2) measured by qPCR. *P < 0.05, **P < 0.01 and ***P < 0.005.
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l1 cell linescauses abnormal physiologicalamino acid derivativeimmune cell functionepididymal fat tissuexlink "> obesitymedical term usedadipocytes high calorie dietfat diet micerebamipide treatment reducedprevent dietimmune cellsadipose tissuefat accumulationweight gaintaken togetherreceiving injectionsrebamipide treatmentrebamipide decreasedprevious studiespathological processesmucosal damagem2 macrophagesm1 macrophagesliver weightinsulin resistanceinflammatory treginflammatory cellsinflammatory activityincreased antieffective methodcontrol micecause pro11 weeks
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