pone.0297625.g005.tif (313.64 kB)
Reactivity of serum antibody against the selected peptides assessed by ELISA.
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posted on 2024-03-05, 18:27 authored by Thi-Tuyet Trinh Tran, Thi-Hong Nhung Nguyen, Yves Dauvilliers, Roland Liblau, Xuan-Hung NguyenEach dot represents an individual sample from the eight patients with other hypersomnolence complaints (OHC) and twenty-six patients with Narcolepsy type I (NT1). Multiple t-test p values are reported for the group comparison between OHC and NT1.
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neurons producing orexinnarcolepsy type 1mediated immunity ratherdifferential binding capacityalso named hypocretinserum immunoglobin gnt1 patient cohortunbiased random peptidespecific antigens targetedohc control groupmer peptides derivednt1 serum iggtargeted methodologiesspecific autoantibodiesvarious peptidesstatistically significantselective lossselected usingrtn4 proteinsprevious studiesorexinergic neuronohcs ).lateral hypothalamushypersomnolence complaintshigh reactivityautoimmune responseautoimmune disease
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