pone.0244768.g003.tif (918.17 kB)
RV echocardiographic evaluation; PAAT/PET-PAAT: Pulmonary artery acceleration time, PET: Pulmonary artery ejection time; S (n = 8): Sedentary Control; SPAH (n = 8): Sedentary Pulmonary Arterial Hypertension; T (n = 8): Control with Training; TPAH (n = 8): Pulmonary Arterial Hypertension with Training.
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posted on 2021-09-08, 17:25 authored by Thaoan Bruno Mariano, Anthony César de Souza Castilho, Ana Karenina Dias de Almeida Sabela, André Casanova de Oliveira, Sarah Santiloni Cury, Andreo Fernando Aguiar, Raisa de Jesus Dutra Dias, Antonio Carlos Cicogna, Katashi Okoshi, Luis Antonio Justulin Junior, Robson Francisco Carvalho, Francis Lopes Pacagnelli* p<0.05 compared to S; # compared to TPAH. One-way ANOVA and Tukey’s post hoc.
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right hypertrophied ventriclesreduced cardiac hypertrophypulmonary arterial hypertensionextracellular matrix remodelingextracellular matrix genesweek adaptation periodencoding proteins associateddiv >< passessed exercise capacity8 ); sedentary8 ); controlweek training periodtpah groups receivedtpah group rats8 );sedentary controlgroups receivedtpah groupspreventive exercisefunctional capacityencoding myosin8 ).13th week11th weekfour groupstranscript abundancetraining protocolspah groupsectional areasreverse transcriptionrats underwentquantitative pcrqpcr ).preventive trainingpah ),myocyte cellsmyh7 kg ).induce alterationsgain insightfulton ’fractal dimensionfindings demonstratefd ).echocardiography analysiscollagen expressioncollagen contentcol1a1 60 mg
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