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RNA-seq analysis of HTLV-1 proviral expression in live-sorted cells of clone Timer-TBX4B.

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posted on 2024-03-01, 18:46 authored by Hiroko Yaguchi, Anat Melamed, Saumya Ramanayake, Helen Kiik, Aviva Witkover, Charles R. M. Bangham

Cells were sorted into four populations based on the fluorescence of the Timer protein, DN–double negative (HTLV-1 silent); blue–early burst; DP double-positive (mid-burst); red–late burst. [11].(A) Coverage tracks in IGV of plus strand HTLV-1 provirus transcription and (B) host gene PNPLA3 transcription. (C) Transcription in PNPLA3 exons 1 and 2 (note range on vertical axis 0 to 500).

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