ppat.1009165.s005.tif (4.17 MB)
RBD-positive memory B cells in donors CoV01-17.
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posted on 2021-02-11, 18:28 authored by Michael Mor, Michal Werbner, Joel Alter, Modi Safra, Elad Chomsky, Jamie C. Lee, Smadar Hada-Neeman, Ksenia Polonsky, Cameron J. Nowell, Alex E. Clark, Anna Roitburd-Berman, Noam Ben-Shalom, Michal Navon, Dor Rafael, Hila Sharim, Evgeny Kiner, Eric R. Griffis, Jonathan M. Gershoni, Oren Kobiler, Sandra Lawrynowicz Leibel, Oren Zimhony, Aaron F. Carlin, Gur Yaari, Moshe Dessau, Meital Gal-Tanamy, David Hagin, Ben A. Croker, Natalia T. FreundFlow cytometry plots showing APC-RBD and PE-RBD double stained memory B cells for CoV01-17 (no PBMCs were obtained for CoV18). The frequencies of double positive B cells are indicated within each plot.
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COVID -19ACEb cell receptorcombination antibody therapyCOVID -19 convalescent donorsB cell responsesMulti-clonal SARS-CoV -2 neutralizationBCRELISAnAbs germline VHJH precursorspatients 1.5 months post SARS-CoV -...block SARS-CoV -2 infectionmulti-clonal neutralizing responsesSpike receptor binding domainRBD
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