pone.0260878.s004.tif (98.3 kB)
Quantitative analysis of mRNA level of palladin-interacting proteins.
figure
posted on 2021-12-08, 18:29 authored by Nadine Artelt, Alina M. Ritter, Linda Leitermann, Felix Kliewe, Rabea Schlüter, Stefan Simm, Jens van den Brandt, Karlhans Endlich, Nicole EndlichA significant downregulation of Vasp mRNA and upregulation of Amotl1 mRNA in PodoPalld129-/- glomeruli was found by qRT-PCR. Data are presented as means ± SD; ** p<0.01; *** p<0.001; unpaired Student’s t-test.
(TIF)
History
Usage metrics
Categories
Keywords
parietal epithelial cells129 genetic backgroundmorphological deviations like12 months showedchronic kidney diseasesbinding protein palladin>, three palladinpodocyte foot processesdiv >< pbinding partners pdlim26 genetic backgroundproper actin cytoskeletonsignificantly reduced expressionproper podocyte morphologypodopalld129 -/- micepodopalld129 -/-podocyte morphologyreduced expressionmorphological changesimportant actinpodopalld129 -/-)kidney dependskidney damageintact morphologypodocyte spacetaken togetherspecific knockoutresults showproteinuria followedpdlim2 marked dilatationinteracting proteinsglomerular tuftfiltration barrierenlarged subclose contactback crossedage showed6 -/-)
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC