ppat.1008618.s003.tif (4.38 MB)
Download fileQuantitation of the γH2AX levels in Fig 1C.
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posted on 2020-05-26, 17:38 authored by Huijun Zhi, Xin Guo, Yik-Khuan Ho, Nagesh Pasupala, Hampus Alexander Anders Engstrom, Oliver John Semmes, Chou-Zen GiamγH2AX levels of HeLa-GΔRNF8 cells transduced with either Ad-GFP (Control) or Ad-RNF8 in Fig 1C were quantified and normalized as above and presented relative to the untreated HeLa-GΔRNF8 cells transduced with Ad-GFP.
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DNA-PKcytosolic K 63-pUbsLUBACAdult T-Cell Leukemiasequester DDR factorsHTLV -1-infected cellsactivates ring finger protein 8Infection Promote Genomic InstabilityBRCAK 63-linked polyubiquitin chainsDSBK 63-M pUbsATLRNF 8 expressionTax activates RNF 8MDCIKKK 63-pUbsK 63-pUb assemblyRNF 8 Dysregulationgenomic instabilityDNA damage responseRNF 8. Tax mutantsTSS
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