pone.0295813.g005.tif (1 MB)

Protein expression.

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posted on 2024-01-09, 18:24 authored by Ruijuan Guan, Zefeng Kang, Ling Li, Xin Yan, Tianpeng Gao

A, Protein expression in each group. B, PI3K expression was the highest in the PIK3CA-wt group, followed by PIK3CA-mut and DR model groups. B, mTOR protein expression was not significantly different between the groups. C, No significant difference was observed in AKT protein expression between different groups. D, VEGF protein expression was the highest in the PIK3CA-wt group, followed by PIK3CA-mut and DR model groups (*, p<0.05).

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underwent physical examination tnf )- α inflammatory factors tnf fetal bovine serum 12 healthy subjects il )- 1β 96 controls ).cell counting kit detected using enzyme high glucose induced high glucose activates twelve patients diagnosed calcium ion pathway mutated snp sites dr model cells detected snp candidates pik3ca regulates development c allele increases dr cell model calcium ion glucose concentration αand il shortlisted candidates patients diagnosed 58 controls 19 cells cell proliferation cell apoptosis cell activity dr increased xlink ">wt vectors vegf proteins vegf throughput sequencing similar age seven snps september 2020 second validation sample size randomly selected qpcr ),pik3ca mutant pik3ca phosphatidylinositol 3 mutated snps medium supplemented mainly enriched kyoto encyclopedia june 2021 including prkce glutamatergic synaptic gene ontology future analysis flow cytometry first validation enrichment analyses empty vector diabetes retinopathy cellular apoptosis case group c allele blood samples biological effects akt pathway 56 patients 2 ml 157 patients

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