Protein-level analysis of mutations of OBSCN and AHNAK2 genes in GBM patients.

a) A lollipop plot illustrating various OBSCN mutations (missense or nonsense) in different domains of the OBSCN protein. b) A lollipop plot depicting various AHNAK2 mutations (missense, nonsense, or frameshift deletions) throughout the AHNAK2 protein. c) The Kaplan-Meier curve for OS analysis between GBM patients with mutations in different domains of the OBSCN protein. d) The Kaplan-Meier curve for OS analysis in GBM patients with mutations in the immunoglobulin domain of the OBSCN protein compared to patients with mutations in other immunoglobulin-related domains. e) The Kaplan-Meier curve for OS analysis in GBM patients with mutations in different segments of the AHNAK2 protein.