Phylogenetic reconstruction of the 88 Mtb isolates from Ecuador.

A total of 5,586 SNPs were used to reconstruct the phylogenetic tree using the maximum likelihood method, the GTR substitution model and a bootstrap cut-off of 0.01. Metadata include i) transmission groups (lines green, yellow, and blue), ii) sublineage classification, iii) global genotypic class of drug resistance and iv) DST results of first- and second-line antibiotics (full circle = resistant; empty circle = sensitive; missing circle = not tested).