pntd.0010151.g001.tif (538.69 kB)
Phylogenetic analysis of Schistosoma haematobium tetraspanins and homologs from related organisms.
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posted on 2022-01-24, 18:39 authored by Gebeyaw G. Mekonnen, Bemnet A. Tedla, Mark S. Pearson, Luke Becker, Matt Field, Abena S. Amoah, Govert van Dam, Paul L. A. M. Corstjens, Takafira Mduluza, Francisca Mutapi, Alex Loukas, Javier SotilloA multiple sequence alignment was carried out using MUSCLE. PhyML was used for a maximum-likelihood phylogenetic analysis with bootstrapping, and results were visualized with The Interactive Tree of Life (iTOF) online phylogeny tool (https://itol.embl.de/) using default parameters.
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provides compelling evidencehost immune systemcirculating anodic antigennovel diagnostic markerslarge extracellular loopsbacterial expression systemurine igg responsesdifferentially expressed throughoutdifferent parasite proteomespotential diagnostic valueschistosoma haematobium diagnostic capabilityhaematobium extracellular vesiclesexpression withinwork presentedurogenital schistosomiasissoluble excretorysh secretory productsrobust associationrecombinant proteinspolyclonal antibodiesmrnas encodingmicroscopy ).low levelsleading causeinternal tissuesimmunologically diagnoseendemic areabladder cancerbiomarker signatureassessed usinganatomical sitesadult parasitesabundantly present>- tsp
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