Performance of methods on simulated eQTL and GWAS datasets.

(A) Estimates of each method over true (simulated) gene-to-trait values. The method denoted with “causal” indicates an inverse variance weighted slope estimation using the true causal SNPs but the estimated coefficients and SEs (an oracle estimate), and “all” indicates an inverse variance weighted slope estimation using all SNPs. (B) Observed coverage (abbreviated “cov.”) of 80% confidence or credible intervals from each method. If the interval contains the true effect size, it is colored black, otherwise red.