pone.0257783.g005.tif (301.92 kB)
Oxygen concentration during end-ischaemic HMP.
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posted on 2021-10-28, 17:29 authored by Hamid Abudhaise, Jan-Willem Taanman, Peter DeMuylder, Barry Fuller, Brian R. DavidsonThis figure shows the pO2 in the perfusate and segments IV and VII during (A) pre-oxygenation, (B) active oxygenation, and (C) post-oxygenation phases.
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static cold storageischaemia reperfusion injuryinduce oxidative damagehypothermic machine perfusionoxygen delivery efficiency001 ), stabilisedp &# 8804mitochondrial respiratory chainmitochondrial function analysismitochondria likely respond28 minutes comparedlower complex iirespiratory functionmitochondrial parametersmitochondrial dysfunctionhour perfusionconsistently loweroxygen supplemented36 minutes3 minutes003 ),xlink ">used clinicallytime measurementsstudy stagesstudy aimedstage 2stage 1respectively ).preservation periodperfusate oxygenparenchymal poorgan steatosishour preservationhighly susceptibledonor historycomplex iicitrate synthase75 vs73 nmol113 nmol05 ).01 ).
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