pone.0241240.g004.tif (436.99 kB)
No gender-specific difference in survival outcomes by CXCR4 expression.
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posted on 2021-01-28, 18:32 authored by Andrea S. Fung, Karen Kopciuk, Michelle L. Dean, Adrijana D’Silva, Shannon Otsuka, Alexander Klimowicz, Desiree Hao, Don Morris, D. Gwyn BebbThere was no difference in recurrence-free survival (top panel) or overall survival (bottom panel) based on gender in patients with high or low levels of CXCR4 expression based on median splits.
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lung carcinogenesisMethods Patient characteristicsCXCR 4 groupsmultivariable analysisstudy quantifies CXCR 4 expressionOSHRlung cancer evolutionGlans-Look Lung Cancercytokine receptor CXCR 4stage non-small cell lung cancer pa...PHConclusions CXCR 4 expression increasesTom Baker Cancer Centrestage diseasecytokine receptors increasesresected stage I-III NSCLC patientsgender-specific recurrence-freegender-specific differencesTMAHazard Ratiostage IV patientssurvival outcomesgender differencestage IV non-small cell lung cancerCXCR 4 expressionMedian RFSCXCR 4 expression increasesTBCCSDResults 176 stage I-III NSCLC patientsMSMtissue microarraysstage NSCLC patientslung carcinogenesis warrant54.5 monthsoutcome dataKaplan-Meier analyses80.9 months vsstage progression52.8 months vsG-LLC
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