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Morphine effects on post-incisional allodynia in mice

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posted on 30.12.2011, 19:18 by J David Clark, Xiaoyou Shi, Xiangqi Li, Yanli Qiao, DeYong Liang, Martin S Angst, David C Yeomans

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Taken from "Morphine reduces local cytokine expression and neutrophil infiltration after incision"

http://www.molecularpain.com/content/3/1/28

Molecular Pain 2007;3():28-28.

Published online 2 Oct 2007

PMCID:PMC2096620.

In these experiments the mechanical withdrawal thresholds of mice were measured before and at two time points after hind paw incision. Mice received saline or various doses of morphine immediately prior to making the incisions. Panel A displays the time course data. Panel B presents the mechanical thresholds for each group as a percent of the threshold for saline treated animals 30 minutes after incision. Panel C presents the mechanical thresholds for each group as a percent of the threshold for saline treated animals 2 hours after incision. Each group contained 5 mice. **p < 0.01 relative to saline treated animals.

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