posted on 2021-03-02, 18:26authored byTimothy C. Stutz, Alfonso Landeros, Jason Xu, Janet S. Sinsheimer, Mary Sehl, Kenneth Lange
Tumor cells grow under a birth-death-migration process. Immune cells immigrate from the barrier at constant rate, migrate to cancer cells, then destroy the cancer cells occasionally producing fibrotic cells after this predation. Fibrotic cells are slightly porous to the immune cells but block the diffusion of the cancer cells. FI stands for a fibrotic cell that has an immune cell currently passing through it.