pone.0256973.g001.tif (103.33 kB)
Metabolic profiling of miR-181c/d-/- (c/d KO) mice.
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posted on 2021-12-08, 18:30 authored by Kei Akiyoshi, Gretha J. Boersma, Miranda D. Johnson, Fernanda Carrizo Velasquez, Brittany Dunkerly-Eyring, Shannon O’Brien, Atsushi Yamaguchi, Charles Steenbergen, Kellie L. K. Tamashiro, Samarjit Das(A) Oxygen consumption (VO2), (B) carbon dioxide production (VCO2), (C) respiratory exchange rate (RER), and (D) energy expenditure (EE) were measured before and during the 26 weeks of high-fat (HF) diet. Data are expressed as mean ± SEM (n = 4/genotype). *p<0.05 by Bonferroni post hoc analysis after intergroup differences were found by 2-way ANOVA. *p<0.05, ****p<0.0001 by two-sample t-test.
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sup >-/-pathophysiological complications associatedisocitrate dehydrogenase 1indirect calorimetric measurementsassociated virus attenuatedseveral genes regulatedinduced cardiac dysfunctiondiv >< pliver triglyceride levels181c might contributelipid synthesis genesqpcr data showedliver wt mice fedlipid synthesisgenes involvedvivo data indicatewt liverliver playsinduced obesityvia adenotaken togetherrecently identifiedquantitative pcrmitochondrial pathwaymice fedmetabolic consequencesinsulin insensitivityhigher serumencoded mirna26 weeks181c delivered
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