Metabolic consequences of high-fat (HF) diet on miR-181c/d^-/- (c/d KO) mice.

(A) Blood glucose and area under the curve during an intraperitoneal glucose tolerance test (IPGTT) and (B) plasma insulin levels and area under the curve during an IPGTT. Data are expressed as mean ± SEM and are from 6–7 mice/genotype/diet. *p<0.05 by Bonferroni post hoc analysis after intergroup differences were found by 2-way ANOVA. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 by two-sample t-test.