pmed.1003679.s003.tif (1.66 MB)

Mendelian randomisation sensitivity analyses for female reproductive disorders regressed on obesity traits.

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posted on 2022-02-01, 18:22 authored by Samvida S. Venkatesh, Teresa Ferreira, Stefania Benonisdottir, Nilufer Rahmioglu, Christian M. Becker, Ingrid Granne, Krina T. Zondervan, Michael V. Holmes, Cecilia M. Lindgren, Laura B. L. Wittemans

(A) Female-specific genetic instruments versus combined-sex genetic instruments. (B) Reproductive outcomes from meta-analysis of UK Biobank and FinnGen summary statistics versus FinnGen only. (C) Genetic instruments from GWASs including UK Biobank participants (Pulit et al. 2019 [34]) versus external genetic instruments from GWASs without UK Biobank participants (GIANT releases, 2015).

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