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Mean intensity quantification of FLAG immunofluorescence in WT and TnTp38γ/δact hearts (Fig 1C) using ImageJ.

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posted on 2021-11-10, 18:30 authored by Ayelén M. Santamans, Valle Montalvo-Romeral, Alfonso Mora, Juan Antonio Lopez, Francisco González-Romero, Daniel Jimenez-Blasco, Elena Rodríguez, Aránzazu Pintor-Chocano, Cristina Casanueva-Benítez, Rebeca Acín-Pérez, Luis Leiva-Vega, Jordi Duran, Joan J. Guinovart, Jesús Jiménez-Borreguero, José Antonio Enríquez, María Villlalba-Orero, Juan P. Bolaños, Patricia Aspichueta, Jesús Vázquez, Bárbara González-Terán, Guadalupe Sabio

Data are mean ± SEM (n = 4–5). ***p < 0.001 by Student t test. Raw data are given in S14 Fig. WT, wild-type.

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    p38 &# 948p38 &# 947maladaptive cardiac pathogenesisglycolytic energy productionglycogen synthase 1glycogen metabolism inactivationcardiomyocyte fuel supplycardiac glycogen productionactivated protein kinasesearly metabolic shiftbody metabolic deregulationmaternal diet supplementationfatty acid oxidationpostnatal heart developmentnewborn mice resultsearly gys1 phosphorylationmetabolic changeresults suggestneonate miceinhibitory phosphorylationfatty acidsdiet interventionsxlink ">premature inductionfirst weeksadverse effects

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