Maximum % of B_M cell responses after WRSs2 & WRSs3 vaccination.

Maximum % of antigen-specific IgG and IgA+ B_M cell responses of each subject after WRSs2/ WRSs3/placebo administration is given on the Y axis and the X axis provides the CFU doses of the vaccine candidates from 10³ to 10⁷ CFU. The antigens used (LPS, IVP and IpaB) are mentioned on the right side of the figure and the isotype (IgA or IgG) of the B_M cell response is indicated at the top. For all doses in both groups of vaccinees, the number of archived samples available were n = 8, except the following; WRSs2 10⁴ CFU for all time points n = 7; WRSs3 10⁴ CFU n = 7, 7, 6 for d-1, d28, d56; WRSs3 10⁵ CFU n = 7 for d56; WRSs3 10⁶ CFU n = 6 for d-1, d28, d56; and WRSs3 10⁷ CFU n = 7 for d-1. For placebo group available samples were n = 9, 8 and 9 at 3 time points.