pone.0261435.g002.tif (3.89 MB)
Maximum likelihood phylogeny of MLST alleles from 216 C. diphtheriae isolates.
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posted on 2021-12-15, 18:36 authored by Naveen Kumar Devanga Ragupathi, Dhiviya Prabaa Muthuirulandi Sethuvel, Dhivya Murugan, Ranjini Ranjan, Vikas Gautam, Prashanth Gupta, Jaichand Johnson, Naresh Chand Sharma, Ankur Mutreja, Pradeep Haldar, Arun Kumar, Pankaj Bhatnagar, Lucky Sangal, Balaji VeeraraghavanThe clades are highlighted based on the common ST types identified in the study. STs associated with non-toxigenic strains are highlighted in yellow. The inner ring represents the toxigenicity results of the isolates followed by date of collection. The outer ring represents the region of isolation.
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standard biochemical testsinternational clone st50div >< pbetter dissemination propertiesantimicrobial susceptibility testingmolecular data generatedepidemiological analysis revealedcommon st identifiedalso provided informationsince diphtheria morbiditytoxigenic strain belongscorynebacterium diphtheriae corynebacterium diphtheria present study aimeddiphtheriae toxigenic bacteriummolecular epidemiologymlst analysisidentified stsc also seentime pcrsurveillance systemsurveillance programmesingle nonsequence typesnovel stsmortality continuesmajority belongsemerging pathogenelek ’divergent evolutiondifferent regionscomplete susceptiblecc5 followedcc ).34 sts30 %).
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