ppat.1009742.s003.tif (2.73 MB)

Marker expression in DC and monocyte subpopulations in patients and controls (related to Fig 4A).

figure

posted on 2021-10-06, 17:47 authored by Elena Winheim, Linus Rinke, Konstantin Lutz, Anna Reischer, Alexandra Leutbecher, Lina Wolfram, Lisa Rausch, Jan Kranich, Paul R. Wratil, Johanna E. Huber, Dirk Baumjohann, Simon Rothenfusser, Benjamin Schubert, Anne Hilgendorff, Johannes C. Hellmuth, Clemens Scherer, Maximilian Muenchhoff, Michael von Bergwelt-Baildon, Konstantin Stark, Tobias Straub, Thomas Brocker, Oliver T. Keppler, Marion Subklewe, Anne B. Krug

Expression of the indicated markers was measured as mean fluorescence intensity values in the indicated cell populations in COVID-19 patients with mild/moderate (M, n = 20) or severe disease (S, n = 6) at the first analysis timepoint compared to healthy donors (H, n = 11). Results for individual patients are indicated by symbols, Box plots show the 25 to 75 percentile; whiskers show the 10 to 90 percentile, horizontal lines indicate the median (Kruskal-Wallis test with Tukey’s or Dunn’s correction, n = * p<0.05, ** p<0.01, *** p<0.001).

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