Male C3H/HeN mice were infected with UTI89 (closed circles) or isogenic, individual UTI89 CUP pili mutants (open diamonds), and organs were harvested 2 wpi.
posted on 2021-01-29, 18:42authored byLisa K. McLellan, Michael R. McAllaster, Arthur S. Kim, Ľubomíra Tóthová, Patrick D. Olson, Jerome S. Pinkner, Allyssa L. Daugherty, Teri N. Hreha, James W. Janetka, Daved H. Fremont, Scott J. Hultgren, Herbert W. Virgin, David A. Hunstad
None of these CUP pili mutants displayed defects in bladder or kidney colonization. Horizontal bars indicate geometric mean, and dotted line indicates limit of detection. n = 6–18 mice per experimental condition over 6 independent experiments.