ppat.1009314.s002.tif (187.2 kB)
Male C3H/HeN mice were infected with CFT073 (closed circles) or CFT073ΔfimH (open diamonds), and organs were harvested (A) 24 hpi or (B) 2 wpi.
figure
posted on 2021-01-29, 18:42 authored by Lisa K. McLellan, Michael R. McAllaster, Arthur S. Kim, Ľubomíra Tóthová, Patrick D. Olson, Jerome S. Pinkner, Allyssa L. Daugherty, Teri N. Hreha, James W. Janetka, Daved H. Fremont, Scott J. Hultgren, Herbert W. Virgin, David A. HunstadNo significant differences in bacterial loads were observed 24 hpi; ΔfimH was attenuated significantly 2 wpi in both the bladder (*p = 0.0482) and kidneys (****p<0.0001). Horizontal bars indicate geometric mean, and dotted line indicates limit of detection. A) n = 10 mice per condition over 2 independent experiments; B) n = 13–14 mice per condition over 3 independent experiments.
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