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Loss of Dif but not Relish results in loss of bacterial density.

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posted on 2022-01-10, 18:27 authored by Shivohum Bahuguna, Magda Atilano, Marcus Glittenberg, Dohun Lee, Srishti Arora, Lihui Wang, Jun Zhou, Siamak Redhai, Michael Boutros, Petros Ligoxygakis

(A) Dif RNAi in enterocytes resulted in a significant reduction in bacterial CFUs. (B) In contrast, loss of Relish resulted in the significant increase of two major components of the intestinal bacteriome namely, Lactobacillus and Acetobacter spp. Statistical comparisons were conducted using student’s t-test (*p<0.1, **p<0.01, ***p<0.001).

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