pntd.0011907.g003.tif (1.47 MB)
Longitudinal seropositivity rates against PE antigens of P. vivax.
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posted on 2024-01-26, 18:21 authored by Pongsakorn Thawornpan, Justin Nicholas, Chayapat Malee, Piyawan Kochayoo, Kittikorn Wangriatisak, Pachara Tianpothong, Francis Babila Ntumngia, Samantha J. Barnes, John H. Adams, Patchanee Chootong(A) Heatmap represents antibody responses against full-length, N-terminal and C-terminal PvCSP-VK210, PvSSP3, PvM2-MAEBL, PvCelTOS, and PvSPECT1 that were determined at four different timepoints (days 0, 90, 270 and 360) in individual P. vivax subjects (n = 20) residing in cohort study. (B) Seropositivity of IgG antibodies against PE antigens at different time points in P. vivax subjects (n = 20). Samples were considered as seropositive if the RI was greater than 1. Dark blue tiles represent seropositive samples at a given timepoint.
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present study demonstratedlow transmission areasknowledge could contributechumphon provinces ).360 days latertested pe antigenspe candidate antigensmultiple pe antigensamong seropositive subjectsplasmodium vivax notably seropositivity persistedleast 360 dayssubjects possessed antibodiesacute vivax malariapvssp3 antibody responsesvivax antibody responsesserological responsesp antibodies declinedxlink ">vaccines emergetropical countriestotal iggresults showedremain detectablepredominant subclasseslongitudinal datalongitudinal analysislongest halfindividuals residingigg subclasseshigh numberattractive approachantigen using
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