pgen.1010582.s002.tif (1.73 MB)
Lack of Sty1 activity further impairs growth of cbf11Δ cells.
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posted on 2023-01-10, 18:29 authored by Jarmila Princová, Clàudia Salat-Canela, Petr Daněk, Anna Marešová, Laura de Cubas, Jürg Bähler, José Ayté, Elena Hidalgo, Martin PřevorovskýExponentially growing WT, cbf11Δ, sty1-as, cbf11Δ sty1-as, and sty1Δ cultures were spotted on YES plates containing 10 μM Sty1-as inhibitor 3-MB-PP1 and incubated for the indicated number of days.
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main pathway respondingcorresponding gene promotersmst1 histone acetyltransferasesschizosaccharomyces pombe pap1 transcription factorshow increased expressionlocalized chromatin hyperacetylationdiv >< presponse gene expressionincreased cellular resistanceatf1 transcription factorconserved sty1 stressgene expressionincreased stressincreased acetylationhistone h3response mechanismsresponse genesregulating transcriptionmga2 cut6 cbf11 specific stresspsychiatric disordersperturbed fattyoxidative stressneurodegenerative diseasesmetabolic statelysine 9lipid metabolismgenes viafission yeastfas inhibitionepigenetic informationdirectly controlcertain metabolitesbecoming apparentalso operateacid metabolismacc /<
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