ppat.1009878.s003.tiff (7.3 MB)

Kinetic of cytokine and chemokine expression in PBMC stimulated by SARS-CoV-2.

figure

posted on 2021-09-02, 17:25 authored by Martina Severa, Roberta A. Diotti, Marilena P. Etna, Fabiana Rizzo, Stefano Fiore, Daniela Ricci, Marco Iannetta, Alessandro Sinigaglia, Alessandra Lodi, Nicasio Mancini, Elena Criscuolo, Massimo Clementi, Massimo Andreoni, Stefano Balducci, Luisa Barzon, Paola Stefanelli, Nicola Clementi, Eliana M. Coccia

Peripheral blood mononuclear cells (PBMC) were left untreated (not stimulated, ns) or stimulated for 24 or 48 hours with SARS-CoV-2 (MOI = 0.04 and MOI = 0.1). (A, B) Production of IL-6 (A), and CXCL-10 and CXCL-9 (B) was tested by multiparametric cytokine bead arrays in collected cell culture supernatants. Shown results were mean relative values ± SEM of 3 independent experiments. P-values were calculated by two-tailed Students’ t-test and were depicted as follows: *p≤0.05; **p≤0.01.

(TIFF)