pone.0259330.g004.tif (140.02 kB)
Kaplan–Meier analysis stratified according to TET1 expression score.
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posted on 2021-11-03, 17:32 authored by Nien-Tzu Liu, Cherng-Lih Perng, Yu-Ching Chou, Pi-Shao Ko, Yi-Jia Lin, Yu-Chun Lin, Cheng-Chang Chang, Yu-Chi Wang, Hung-Sheng Shang, Tai-Kuang ChaoAnalysis to assess the prognostic value of the TET1 immunoreactivity in relation to OS.
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good overall survivalcommon gynecological cancerbased retrospective reviewpremalignant endometrial lesionshigh 822111 8211potential prognostic markerpotential histopathology biomarkertet1 mrna levels8 %, respectively0 %, respectivelytet1 mrna expressionhmc expression profiles181 endometrial samplesroutinely used biomarkereleven translocation 1tet1 ihc scoringhigher tet1 scorehmc expression scoremc expression scorehmc expression scoresprognostic biomarkereleven translocationhmc expressionendometrial carcinogenesis 8220significantly higherimmunohistochemical expressionbiomarker determinations1 %)tet1 immunohistochemistryespecially tet1hmc ).via conversionsignificant rolenormal tissuesnormal endometriumhighly proportionalhazard ratiofindings suggestdna demethylationdifferential diagnosisconfidence intervalatypical hyperplasia84 ).4 %)0037 ).001 ).
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