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K-means clustering of the means of expression levels of DEGs in clusters identified in RBC and IT4var14 co-culture with HBMEC without prior TNF activation.

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posted on 2023-11-30, 19:06 authored by Basim Othman, Leo Zeef, Tadge Szestak, Zineb Rchiad, Janet Storm, Caroline Askonas, Rohit Satyam, Aymen Madkhali, Michael Haley, Simon Wagstaff, Kevin Couper, Arnab Pain, Alister Craig

K-means clustering of the means of expression levels of DEGs in clusters identified in RBC and IT4var14 co-culture with HBMEC without prior TNF activation.

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    pathways previously foundprotein called pfemp1human malaria specieshost immune systemdiv >< pinfected erythrocyte membranedifferent pfemp1 variantsplasmodium falciparum human malaria parasitedifferent pfemp1p falciparum severe malariamalaria infectioninfected erythrocyteserythrocytes infectedvascular endotheliumtranscriptional profilesevere diseasemorbidity causedhost microvasculatureendothelial receptorsdifferential engagementbarrier integrityadhesive domains

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