pone.0251216.g002.tif (225.8 kB)
Investigation for ADAMTS13 in 45 patients with HLH.
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posted on 2021-08-03, 17:40 authored by Sandrine Valade, Bérangère S. Joly, Agnès Veyradier, Jehane Fadlallah, Lara Zafrani, Virginie Lemiale, Amélie Launois, Alain Stepanian, Lionel Galicier, Claire Fieschi, Adrien Mirouse, Jean Jacques Tudesq, Anne-Claire Lepretre, Elie Azoulay, Michael Darmon, Eric Mariotte(A) Each patient is represented by an icon; ADAMTS13 activity and ADAMTS13 antigen levels are represented in the same graph; the upper limit of normal ranges are represented as red lines; medians and IQR are represented as black lines. (B) Correlation curve between ADAMTS13 activity and ADAMTS13 antigen.
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PAISepsis-Related Organ Failure Assessmenttissue plasminogen activatoroutcome implicationsDecember 2018. Coagulation assessmentsfibrinogen levelSOFA scoreprothrombin timeADAMTS 13 activityConclusions Hyperfibrinolysisday 1PTHLH-related coagulation disordersResults Coagulation disorderscoagulation disordersADAMTS 13 degradationhospital mortalityfibrin monomersCoagulation disordersplasmin systemhemophagocytic lymphohistiocytosisThromboSpondin type 1hemophagocytic lymphohistiocytosis ...plasminogen activator inhibitorApril 2015day 1.multivariable analysis
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