Injection of pseudo-sarcoids with iNSA/E6E7^equ and iNSB/E6E7^equ induced a systemic immune response.

Injection of pseudo-sarcoids with iNSA/E6E7^equ or iNSB/E6E7^equ (“active substance”) on the left side of the neck induced oedema at the injection sites, and importantly, also at the non-injected tumour sites on the right side of the neck. Intralesional administration of SNH-buffer at the left side of the neck of control horses had no apparent effect, except for short-lived oedema in one horse (not shown). Pseudo-sarcoids on the right side of the neck of control horses remained unchanged.