Impact of antioxidants or H₂O₂ on the mRNA level of ApoB.

(A) Huh-7 cells were infected with HCV (MOI = 1) for 4 days followed by NAC (1 mM) and PDTC (100 μM) treatment for 24 hours. The mRNA level of ApoB was analyzed by qPCR. (B) Huh-7 cells were treated with H2O2 for 24 hours. The mRNA level of ApoB was analyzed by qPCR. The results are presented as fold changes in the mRNA level of ApoB relative to that of GAPDH. The data are shown as the means ± SDs of n = 3 biological repeats. The statistical significance was determined by unpaired two-tailed Student’s t-tests. n.s., not significant. * P < 0.05. ** P < 0.01.

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