pntd.0008586.g008.tif (2.88 MB)
Immune effector networks.
figure
posted on 2020-10-05, 17:24 authored by Federica Fratini, F. Tamarozzi, G. Macchia, L. Bertuccini, M. Mariconti, C. Birago, A. Iriarte, E. Brunetti, CM. Cretu, O. Akhan, M. Siles-Lucas, A. Díaz, Adriano CasulliThe STRING networks corresponding to the GO Term “Immune effector” for APhs (81 proteins; FDR = 9.45E-35) and IPhs (55 proteins; FDR = 7.62E-24) are shown. Besides the different number of proteins involved in the two networks, the term results highly enriched in both datasets but the signalling is based on different proteins: Src, Lyn and certain Integrins (ITGAV, ITGAM, ITGAL) in APhs vs Cdc-42, several Rab proteins and Annexin 2 in IPhs.
