ICG-001 reduces the level of survivin mRNA in MDA-MB-231 cells.

A) MDA-MB-231 cells were treated with DMSO or 3 or 6 μM ICG-001 for 72 h before collecting cells for mRNA extraction. qPCR for surviving was performed on the subsequent cDNA using RPLP0 as a control. Relative survivin mRNA was normalized using RPLP0 and compared to levels in DMSO-treated cells. (n = 2, ***P<0.001, One-way ANOVA with Dunnett post-hoc using DMSO as control).

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