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Hierarchical two-dimensional clustering of recurrent events in cuKA and cuSCC.

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posted on 2021-08-16, 17:38 authored by Aziz Aiderus, Justin Y. Newberg, Liliana Guzman-Rojas, Ana M. Contreras-Sandoval, Amanda L. Meshey, Devin J. Jones, Felipe Amaya-Manzanares, Roberto Rangel, Jerrold M. Ward, Song-Choon Lee, Kenneth Hon-Kim Ban, Keith Rogers, Susan M. Rogers, Luxmanan Selvanesan, Leslie A. McNoe, Neal G. Copeland, Nancy A. Jenkins, Kenneth Y. Tsai, Michael A. Black, Karen M. Mann, Michael B. Mann

Hierarchical two-dimensional clustering (Hamming distance with the Ward method of agglomeration) of recurrent genic SBCapSeq insertion events from four skin masses containing distinct cuKA and cuSCC regions. Four distinct specimen (x-axis) and gene (y-axis) clades, each pertaining to a single bi-lesional mass, demonstrate clonal identities. Zmiz1 was the only gene recurrently mutated across all samples with high read depths, highlighted in blue text.

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