pone.0262293.g004.tif (457.23 kB)
HRs for combined-DOACs vs. warfarin by propensity score methods.
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posted on 2022-01-24, 18:27 authored by Giorgio Ciminata, Claudia Geue, Olivia Wu, Manuela Deidda, Noemi Kreif, Peter LanghorneNote: DOACs = Direct Oral Anticoagulants, PS = Propensity Score, PSM = Propensity Score Matching, IPTW = Inverse Probability of Treatment Weighting (IPTW), Inverse Probability of Censoring Weighting (IPCW).
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unobserved confounding holdprescribing information systeminverse probability weightinghealth technology assessmentexplore methodological challengesdirect oral anticoagulantstreatment effect tendssmaller sample sizesfirst clinical eventpatients &# 8217newly anticoagulated patientsxlink "> overallused linkage databest performing methodassessing covariate balanceps based methodspropensity score methodsxlink ">propensity scoreps methodstreatment switchingsample sizegood balancecovariate adjustmentclinical outcomesworld evidenceversus warfarinusing realstandardised differencemultiple approachesmodel performancemajor bleedingipcw approachincluding apixabancase study2 years
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