pntd.0009940.s004.tif (600.69 kB)
HAM/TSP present lower MFI.
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posted on 2021-11-12, 18:36 authored by Brenda Rocamonde, Nicolas Futsch, Noemia Orii, Omran Allatif, Augusto Cesar Penalva de Oliveira, Renaud Mahieux, Jorge Casseb, Hélène DutartreMedian intensity fluorescence (MFI) of the cytokine expression for dendritic cell (A) and monocytes (B) subsets after TLR7 stimulation in AC and HAM/TSP patients. One-way ANOVA followed by Sidak’s correction for multiple comparisons was applied.
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tropical spastic paraparesissup >+pdc producing ilcell leukemia virushigher ifnγ responsivenessdevastating neurodegenerative diseasemonocytes producing mipincluding asymptomatic carriersdiv >< ptsp patients comparedtsp blood samplesblood samplesasymptomatic carrierstsp patientstsp comparedhigher frequencydisease occurrencedisease manifestationsteady statesignaling pathwaypotential consequencenk cellsneuroinflammatory statusmechanism underlyinglower responselike receptorinflammatory responseinfected volunteersincreasing numberincreased sensitivityimmune cellseffective treatmentcorticosteroid treatmentsadaptive compartment
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