Granuloma IFP estimates and comparisons to tumor data.

(A) Predicted dimensionless IFP profiles within granulomas from the uniform perfusion case for varying values of dimensionless granuloma size, α₀ = 1–15. (B) Fitting the theoretical IFP estimates (Eq III with a fitted modulus [9], see S1 Text) to experimentally measured tumor IFP data (from human neuroblastoma tumor models grown in immunosuppressed rats, ~2 cm in diameter [9]) demonstrates the applicability of the uniform perfusion model to physiological IFP levels with a single fitted parameter.