pone.0256451.s003.tif (307.98 kB)
Genome-wide site-by-site selection pressure analysis for sequences from GH clade.
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posted on 2021-08-31, 17:24 authored by Najia Karim Ghanchi, Asghar Nasir, Kiran Iqbal Masood, Syed Hani Abidi, Syed Faisal Mahmood, Akbar Kanji, Safina Razzak, Waqasuddin Khan, Saba Shahid, Maliha Yameen, Ali Raza, Javaria Ashraf, Zeeshan Ansar, Mohammad Buksh Dharejo, Nazneen Islam, Zahra Hasan, Rumina HasanSelection pressure (relative number of non-synonymous substitutions minus synonymous substitutions (dN–dS)) on each codon is shown.
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would likely leadsup >&# 8722spike glycoprotein d614gmatched pakistani isolatesislamabad capital territoryoverall higher meanrna substitution ratesglobal strains exceptstudied ninety sars36 ), lhigher across ghwhole genome sequencesjune 2020 exhibited2 genomes clusteredpakistan higher entropy observed4 ), v2 strains isolatedhigher entropystrains isolatedmutation ratesgenome diversity2 strains2 gh2 genomesspecific entropyrelative entropystrains belonginggh strainsxlink ">transmitted locallysubsequent covidspecific changespunjab provinceoverseas travelersorf3a q57hoctober 2020investigate phylogenyinvestigate evolutioninitial introductionshighest diversitygenetic variantionfrequent mutationsfirst covidearly pandemicearly coviddiversity observedcurrently observedavailable genomes86 x1019 waves19 wave19 period
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