General structure of the two-compartments model.
figureposted on 2016-08-02, 17:30 authored by Mauro Pietribiasi, Jacek Waniewski, Alicja Załuska, Wojciech Załuska, Bengt Lindholm
Plasma and interstitial compartments are separated by the porous capillary membrane, in which 3 types of pores are present, LP, SP, UP (large, small and ultrasmall pores). Bi-directional transport of fluid and proteins happens across the membrane through the pore system (but UP are not permeable to proteins), and is complemented by a reabsorption of fluid and solute through the lymphatic vessels. Water is removed from vascular compartment by the HD machine.