pone.0260770.g002.tif (1.79 MB)
Flow diagram showing patient inclusion, randomization and follow-up in the OPTIMAL trial.
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posted on 2022-01-07, 18:34 authored by Giovanni Luigi De Maria, Luca Testa, Jose M. de la Torre Hernandez, Dimitrios Terentes-Printzios, Maria Emfietzoglou, Roberto Scarsini, Francesco Bedogni, Ernest Spitzer, Adrian Banning(IVUS: intravascular ultrasound; LAD: left anterior descending; LCx: left circumflex; LM: left main; MI: myocardial infarction; PCI: percutaneous coronary intervention; SAE: serious adverse event; ULMCA: unprotected left main coronary artery).
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standard qualitative angiographyprovide definitive evidenceprimary outcome measureoriented composite endpointacademic research consortiumprocedural ivus assessmentestablish whether ivussuperior clinical outcomesleft main pci2 years followoptimal trial aimsivus guidance armunprotected lmca diseaseguided pci optimizationinternational study designedguided armunprotected lmca2 yearsguided pcistudy protocolgroup studyclinical trialsclinical impactstrategy guidedguided strategyxlink ">whilst postused increasinglysubgroup analysessafety concernspredefined criteriapossible benefitoptimal trialobservational studiesmyocardial infarctionintravascular ultrasoundindex procedurehighly recommendedcause death
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