Fig 3 -

Adjusted incidence rates of cardio-kidney events (A), overt dementia (B), and all-cause death (C) according to the presence of risk factors. The incidence rates and 95% CIs (error bars) in on-treatment SBP categories (90–104, 105–114, 115–124, 125–134, 135–144, 145–154, 155–164, or 165–200 mm Hg) were calculated by multiplying the adjusted hazard ratios and their 95% CIs by a constant to make the sum of the products of incidence rates and person-years in SBP categories equal the total number of observed events. The SBP category 90–104 mm Hg is excluded from the plots. The hazard ratios were adjusted for age, sex, onset year of hypertension, history of cardiovascular disease, antihypertensive, hypoglycemic, and statin treatment statuses, untreated SBP, fasting blood glucose, total and HDL cholesterols, estimated glomerular filtration rate, albuminuria, body mass index, waist circumference, income level, smoking status, exercise frequency, and drinking amount. The SBP 125–134 mm Hg was set as the reference. CI, confidence interval; SBP, systolic blood pressure.