pone.0279085.g003.tif (1.03 MB)
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posted on 2022-12-30, 19:04 authored by Ivana R. Sequeira, Wilson Yip, Louise W. Lu, Yannan Jiang, Rinki Murphy, Lindsay D. Plank, Garth J. S. Cooper, Carl N. Peters, Benjamin S. Aribsala, Kieren G. Hollingsworth, Sally D. PoppittTime course (mean ± SEM) of blood biomarkers during each 30 minute square-wave hyperglycaemic step of the intravenous glucose tolerance test in all women (A-D—open circle, dash lines) in defined low and high percentage pancreatic fat (PPF) groups (E-H) and as change from baseline (I-L). MR-determined PPF groups are as follows: E-L; ≥ 4.5% pancreatic fat–solid diamond, solid line, < 4.5% pancreatic fat–open triangle, solid line.
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visceral adipose tissuelow (< 4insulin secretion ratebiphasic insulin secretionsecond phase isrquantified pancreatic fatdysglycaemia may warrantbaseline analyte concentrations04 units lowerppf x timelow ppf groupshigh ppf valueshigh (≥ 40001 ), insulininsulin secretionpancreatic fatppf maytwo groupst2dm ),given timedysglycaemia basedxlink ">without t2dmwave stepsvs using 25significantly associatedsalient featurepreliminary investigationplasma glucosemin squareincremental areasincreased significantlyhyperglycaemia generatedhence dataethnic differencesemerging roleearly stagescompare changesclinical importancebody compositionassociated decreaseassessed isranthropomorphic variables47 %)05 ).&# 8805
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