Fig 1 -

(A,B) Schematic of 2D Voronoi model (green, degrees of freedom are cell center) and 2D vertex model (purple, degrees of freedom are cell vertices). (C,D) Snapshot of the 3D Voronoi model (green) and vertex (purple) simulations with a heterotypic interface between light and dark cells. (E) Demixing behavior of the 3D Vertex model initialized in a mixed state with DP ≈ 0. The color represents different values of the heterotypic interfacial tension: σ = 0.1 (light pink), σ = 0.2 (medium purple), σ = 0.5 (dark magenta). (F) Demixing as a functional of initial conditions between 3D Vertex and Voronoi models. The dark green (Voronoi) and dark magenta (vertex) are initialized in a sorted state and remain sorted. The bright green (Voronoi) and light pink (vertex) are initialized in a mixed state and rapidly sort.