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posted on 2021-01-20, 18:45 authored by Shahinaze A. Fouad, Fady A. Malaak, Mohamed A. El-Nabarawi, Khalid Abu Zeid, Amira M. Ghoneim

Scanning electron micrographs of pure DCN (a) and the optimized SD (b).

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Preparation of solid dispersion systems for enhanced dissolution of poorly water soluble diacerein: In-vitro evaluation, optimization and physiologically based pharmacokinetic modeling
PLOS ONEPLOS ONE

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dissolutionDCNBCS II compoundvivo plasma concentration time curvespharmacokinetic modeling DiacereinSolid dispersion systemsPKXRDDSCoptimized SDBCS II APIsSEMMDTI-Optimal factorial designDEDCPBPKmin

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