Expression of PTEN-WT in the posterior compartment of the wing disc supressed PI3K/Akt signalling.

Representative images of imaginal wing discs of 3^rd instar larvae stained with anti-GFP to visualize tGPH, a fluorescent sensor of PIP₃ levels [74] (A,B) anti-pAkt (A’,B’) and anti-PTEN (A”,B”) for attp2 and PTEN-WT. Expression of PTEN-WT leads to suppression of both PI3K-induced PIP₃ and pAkt levels in the posterior compartment of the wing imaginal disc.

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